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Prime-time animated television changed the perception of what cartoons could be. This panel explores how shows like The Simpsons and Family Guy helped transform animation into a vehicle for satire, social commentary, and long-form storytelling aimed at general audiences rather than children. Moderated by voice actor Eric Bauza (Bugs Bunny, Daffy Duck), panelists include director Cecilia Aranovich (Harley Quinn, Bob’s Burgers), supervising producer Mike Hollingsworth (BoJack Horseman, Tuca & Bertie), producer Monica Mitchell (Rick and Morty, South Park: Bigger, Longer & Uncut), John Semper (Spider-Man: The Animated Series, Justice League Action),and production designer/colorist Carol Wyatt (Rick and Morty, The Simpsons).